1997

1/14/97

Brian

Matthews

Structural and Genetic Analysis of the Protein Folding Problem.

1/21/97

Roel

Nusse

Biochemical and Genetic Approaches to Wingless Signalling in Drosophila.

1/28/97

Peter

Walter

Intracellular Signaling from the ER to the Nucleus.

2/04/97

Suzanne

Pfeffer

Proteins that Mediate Receptor Trafficking and Organelle Localization.

2/11/97

Arthur

Horwich

Chaperonin/Mediated Protein Folding.

2/18/97

Ruth

Lehmann

Establishment of Embryonic Polarity During Drosophila Oogenesis.

2/25/97

Roger

Kornberg

RNA Polymerase II Transcription: Structure, Mechanism, and Regulation.

3/04/97

Francine

Perler

Protein Splicing: Mechanism and Implications for Protein Engineering.

3/05/97

Eloy

Rodriguez

The Restless Graduate Student in the Rainforest: From Drug/Discovery to Self/Discovery.

3/11/97

Eric

Olson

Molecular Control of Cardiovascular Development

3/18/97

Christopher

Walsh

The Molecular Mechanism of Bacterial Resistance to the Vancomycin Group of Glycopeptide Antibiotics.

3/25/97

James

Rothman

Intracellular Transport and Synaptic Transmission.

4/01/97

Robert

Kingston

Moving Through Chromatin.

4/08/97

Vivek

Malhotra

Membrane Assembly in Organell Biogenesis.

4/15/97

Cliff

Tabin

Coordinating the Dorsal/Ventral and Proximal/Distal Axes of the Limb.

4/21/97

John

Kilmartin

Functional Analysis of Yeast Spindle Pole Body Components.

4/29/97

Nobutaka

Hirokawa

The Mechanism of Organelle Transports in the Cell: Molecular Cell Biology of Kinesin Superfamily Proteins, KIFs.

5/06/97

Heidi

Hamm

G/Protein Structure and Function.

5/13/97

Chris

Doe

Asymmetric Cell Division in the Drosophila CNS.

5/20/97

David

Drubin

The Actions and Interactions of Actin in Budding Yeast.

5/27/97

William

Newsome

Making Decisions: The Brain’s Link Between Perceptions and Action.

6/03/97

Ronald

Evans

Nuclear Receptors: A Superfamily

6/10/97

Jack

Horner

Reconstructing the Life and Habits of Tyrannosaurus Rex

6/17/97

Joseph

Schlessinger

Cellular Signaling by Tyrosine Phosphorylation

9/16/97

Bruce

Stillman

Cell Cycle Control of the Initiation of DNA Replication in Eukaryotes

9/23/97

David

Lockhart

Genomics and DNA Chips

9/30/97

John

Abelson

tRNA Splicing in Eukaryotes and Archea: An Ancient Process

10/07/97

Lynn

Cooley

The Actin Cytoskeleton During Drosophila Oogenesis

10/14/97

Ariel

Ruz i Altaba

Gli Gene Function and SHh Signaling in Neural and Epidermal Development

10/21/97

Tom

Scanlan

Ligand/based Approaches to Nuclear Receptor Signaling`

10/28/97

Spyro

Artavanis-Tsakonas

Notch Signaling

11/04/97

Joan

Steitz

A Tale of Two Spliceosomes

11/11/97

Michael

Grunstein

Histone Deacetylases and Their Function in Yeast

11/18/97

Norbert

Perrimon

Drosophila Signal Transduction Pathways that Regulate Morphogenesis

11/25/97

Mary

Beckerle

Roles of LIM Domain Proteins in Cytoskeletal Organization and Nuclear Cytoplasmic Communication

12/02/97

Michael

Rosbash

RNA/Protein Interactions: Yeast, Mammals and Branchpoint Sequence Recognition

12/09/97

Vishva

Dixit

Identification of Components of the Death Pathway

12/16/97

Karolin

Luger

X/ray Structure of the Nucleosome Core Particle

1/06/98

Nancy

Craig

Tn7: A Smarter Transposon

1/13/98

John

Gerhart

A Discussion of the Cellular and Developmental Bases for Animal Evolution

1/20/98

Linda

Buck

Unraveling Smell

1/27/98

Pernille

Roth

Genetic Control of Differentiation and Cell Migration

2/03/98

Allan

Bradley

Haploid Mice and Tumor Suppressors

2/10/98

Peter

Klein

Bipolar Frogs: Activation of Wnt Signalling by Lithium

2/17/98

Sean

Burgess

Dynamic Interactions Between Homologous Chromosomes during the Cell Cycle in Yeast

2/24/98

Doug

Melton

Development of the Endoderm and Pancreas

3/03/98

Eric

Karsenti

Self Organization and Phosphorylation Gradients as Morphogenetic Principles in Spindle Assembly

3/10/98

Jeffrey

Kelly

Biophysical Studies Suggest A New Small Molecule Therapeutic Strategy for Intervention in Human Amyloid Disease

3/17/98

B. Brett

Finlay

Enteric Bacterial Pathogen Exploitation of Host Cell Functions

3/24/98

Lenny

Guarente

A Molecular Cause of Aging

4/07/98

Peter

Kim

Invasion of Cells by Viruses

4/14/98

Paul

Sigler

Infinite Dilution at High Concentration: Mechanisms of Chaperonin Assisted Protein Folding

4/21/98

Kai

Simons

Lipid Rafts in Membrane Trafficking and Signalling

4/28/98

Bruce

Bowerman

Cell Polarity and Cell Fate in Early C. elegans Embryos

5/05/98

Michael

Botchan

DNA Replication and Chromosome Dynamics: Lessons from Drosophila and Papilloma Virus

5/12/98

Charles

Zuker

G Protein Signaling: Lessons from Drosophila

5/19/98

John

Kuriyan

Structural Studies on Growth Factor Signaling

5/26/98

Tim

Tully

Discovery of Genes Involved with Memory

6/02/98

David

Botstein

Of Genes and Genomes

6/09/98

Randy

Schekman

Protein Sorting and Vesicle Morphogenesis Early in the Secretory Pathway

6/16/98

Lawrence

Zipursky

Axon Guidance in the Drosophila Visual System

9/22/98

Lewis C.

Cantley

Role of PI 3/Kinase in Cellular Regulation

9/29/98

Don C.

Wiley

Structural Studies of Viral Entry in Influenza, HIV /1, and Ebola Virus

10/6/98

Barry

Gumbiner

Cadhernins and Catenins in Cell Adhesion, Signaling,a nd Morphogenesis

10/13/98

Mike

O’Donnell

Protein Dynamics During Chromesome Replication

10/20/98

James T.

Kadonaga

Chromatin Structure and Assembly and the Regulation of Transcritpion by RNA Polymerase II

10/27/98

Erikki

Ruoslahti

Vascular Targeting

11/3/98

Peter

Novic

The Exocytic Machinery of Yeast

11/10/98

Stephen

Sprang

Structure and Regulation of Adenylyl Cyclase

11/17/98

Steve

McKnight

New Pas Domain Proteins/New Places and New Biology

11/24/98

Eric R.

Kandel

Genes, Synapses and Long/Term Memory

12/1/98

Bill

Dove

Genetic, Cellular, and Tissue Interactions in Intestinal Neoplasia

12/8/98

Joachim

Li

Cell Cycle Restraints on Eukaryotic DNA Replication

12/15/98

Lucy

Shapiro

Regulation of Differentiation During the Cell Cycle

1/12/99

Gary

Karpen

Centomere Structure and Function in Drosophila

1/19/99

Mike

Levine

Transcriptional Control of Drosophila and Ciona Embryogenesis

1/26/99

Stephen

Bell

Protein Complex Assembly at Eukaryotic Origins of Replication

2/2/99

Hiten

Madhani

Developmental Specificity of MAPK Signaling in Fungi

2/16/99

Kim

Nasmyth

Separating Sister Chromatids

2/23/99

James

Berger

Molecular "Sleight /of/ Hand": Mechanism and Structure of Type II Topoisomerases

3/2/99

Lawrence

Goldstein

Genetic Analysis of Intracellular Transport in Flies and Mice.

3/9/99

Tatsuya

Hirano

Chromosome Mechanics: from Bacteria to Vertebrates

3/16/99

Martin

Gellert

DNA Mobility in the Immune System: V(D) J Recombination, Transposition, and Translocation

3/23/99

Harry

Orr

Nuclear Alterations in a Polglutamine/Induced Neurodisease

3/30/99

Trina

Schroer

Dynein, Dynactin and Organelle Motility

4/6/99

Gerald

Rubin

Understanding the Drosophila Genome

4/13/99

Frederick

Ausubel

Pseudomonas aeruginosa: A Multi/host Pathogen of Plants, Nematodes, Insects, and Mice

4/20/99

Kathleen

Collins

Assembly and Activity of Telomerase RNPs: from Biochemistry to Disease

4/27/99

Kai

Zinn

Tyrosine Phosphorylation and Axon Guidance in Drosophila

5/4/99

Scott

Emr

Phosphoinositide Signaling, Membrane Traffic and Tumor Progression

5/11/99

Rudolf

Jaenisch

Epigenetic Regulation in Mammalian Development

5/18/99

Jennifer

Lippincott/Schwartz

The Endoplasmic Reticulum is an Intermediate for Golgi Complex Dissolution and Formation in Interphase and Mitosis

5/25/99

Alan

Grossman

DNA Replication and Bacterial Chromosome Partitioning

6/1/99

Sally

Zigmond

Regulation of Actin Polymerization in Leukocytes

6/8/99

Aaron

Turkewitz

Genetics Goes Ballistic: Analysis of Regulated Polypeptide Secretion in Tetrahymena

6/15/99

Frances

Brodsky

The Mystery of the Clathrin Basket Case

9/21/99

Ari

Helenius

CANCELLED

9/28/99

Gebhard

Schertler

Structure of Rhodopsin

10/5/99

Elliot

Meyerowitz

Molecular Mechanisms of Cell/Cell Communication in Plant Development

10/12/99

Douglas

Rees

Structure of a Gated Mechanosensitive Channel

10/19/99

Susan

Marqusee

Touring the Landscape: A Dissection of Protein Folding and Stability

10/26/99

Virginia

Walbot

Developmental Regulation of Mutator Transposons of Maize

11/2/99

Bertil

Daneholt

Assembly and Transport of a Specific Pre/MRNP Particle

11/9/99

Daniel

Klionsky

Targeting of Proteins and Organelles from the Cytoplasm into the Vacuole in Yeast

11/16/99

Dan

Gottschling

Dancing at the End: The Dynamics of Telomere Maintenance in Yeast

11/23/99

Sandra

Schmid

Dynamin Regulation of Endocytosis

11/30/99

Yuh Min

Chook

Structure of the Karyopherin B2/Ran Nuclear Transport Complex: Dropping Off Cargo in the Nucleus

12/7/99

Barbara

Meyer

Sex and Death in C. elegans

12/14/99

David

Julius

Ouch! The Molecular Biology of Peppers and Pain