Ignacio Zuleta

Contact information

Office: 401D

Phone:

Fax: (415) 514-4242

email: Ignacio.Zuleta-at-ucsf.edu

 

 
RESEARCH INTERESTS
Research Description: My main research interest lies in the area of construction of dynamical models that describe the measured transient behavior of transcriptional networks in-vivo. In particular, I am interested in the application of control and information theory to the design of optimal stimulus-response experiments in live cell populations. As a part of this endeavor, I mainly lead an effort to develop new technologies to measure protein expression and population dynamics transients in yeast cells at the genome level. Based on the experimental transient data, I am interested in the systematic learning of dynamical models that help explain the causality and hierarchic relationships between different major signaling pathways at play in yeast when it undergoes stress, aging, nutrient starvation and ecological competition.
Refereed Publications:
"Micromachined Bradbury-Nielsen Gates," Zuleta, I.A.; Barbula, G.K.; Yoon, O.K.; Robbins, M.D.; Zare, R.N. Analytical Chemistry 2007, 79(23), 9160-9165.
“Continuous two-channel time-of-flight mass spectrometric detection of electrosprayed ions ,” Trapp, O.; Kimmel, J.R.; Yoon, O.K.; Zuleta, I.A.; Fernandez, F.M.; Zare, R.N. Angewandte Chemie - International Edition 2004 v.43, no.47, p.6541-6544.
"Novel pteridine alkaloids from the sponge Clathria sp ," Zuleta, I.A.; Vitelli, M.L.; Baggio, R.; Garland, M.T.; Seldes, A.M.; Palermo, J.A. Tetrahedron 2002; v.58, no.22, p.4481-4486.
"Discorhabdins S, T, and U, new cytotoxic pyrroloiminoquinones from a deep-water Caribbean sponge of the genus Batzella Gunasekera, S.P.," Zuleta, I.A.; Longley, R.E.; Wright, A.E.; Pomponi, S.A. Journal of Natural Products 2003; v.66, no.12, p.1615-1617.