Jocelyn Grunwell

Research Interests:

Characterization of the proteins in spliceosome assembly.

Publications:

D'Orso I, Grunwell JR, Nakamura RL, Das C, Frankel AD. (2008) Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes. J Virol. 82(19):9492-504.

Grunwell JR, Das C., Xie B, Nakamura R, and Frankel AD. (in preparation) Mechanism of dominant negative inhibitors of Tat-mediated transactivation on the HIV-1 LTR.

Luchansky SJ, Hang HC, Saxon E, Grunwell JR, Yu V, Dube, DH and Bertozzi CR (2003). Constructing azide-labeled cell surfaces using polysaccharide biosynthetic pathways. Methods Enzymol, 362, 249-72.

Grunwell JR, Rath VL, Rasmussen J, Cabrilo Z, Bertozzi CR (2002). Characterization and mutagenesis of Gal/GlcNAc-6-O-sulfotransferases. Biochemistry. 41(52):15590-600

Grunwell JR, Bertozzi CR (2002). Carbohydrate sulfotransferases of the GalNAc/Gal/GlcNAc6ST family. Biochemistry, 41(44), 13117-26.

Grunwell JR, Glass JL, Lacoste TD, Deniz AA, Chemla, DS and Shultz, PG (2001). Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer. J. Am Chem. 123, 4295-4303.

Deniz AA, Dahan M, Grunwell JR, Ha T, Faulhaber AE, Chemla DS, Weiss S, and Shultz, PG (1999). Single-pair fluorescence resonance energy transfer on freely diffusing molecules: Observation of Förster distance dependence and subpopulations. PNAS 96, 3670-3675.

Siegel MD, Hahn PJ, Dressman BA, Fritz JE, Grunwell JR and Kaldor SE (1997) Rapid purification of small molecule libraries b lon exchange chromatography, Tetrahedron Lett., 38, 3357.

Mrksich M, Grunwell JR and Whitesides GM (1995). Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. J Am Chem Soc, 117, 12009.

Grunwell JR, Wempe MF, Mitchell J, (1993) The transannular rearrangement of 5-cyclodecyone, Tetrahedron Lett, 34, 7163.