Herskowitz Full Bibliography (182 pubs, chronological)
Herskowitz I. and
E. R. Signer (1970). A site essential for expression of all late genes
in bacteriophage lambda. J. Mol. Biol. 47:545-556.
Herskowitz I. and E.R. Signer (1970). Control of transcription from
the r strand of bacteriophage lambda. Cold Spring Harbor
Symp. Quant. Biol. 35:355-368.
Georgopoulos C.P. and I. Herskowitz (1971). Escherichia coli
mutants blocked in lambda DNA synthesis. In: The Bacteriophage
Lambda A.D. Hershey ed. Cold Spring Harbor Laboratory Press Cold Spring
Harbor NY pp. 553-564.
Herskowitz I. (1973). Control of gene expression in bacteriophage
lambda. Ann. Rev. Genetics 7:289-324.
Herskowitz I. and E.R. Signer (1974). Substitution mutations in
bacteriophage lambda with new specificity for late gene expression.
Virology 61:112-119.
Botstein D. and I. Herskowitz (1974). Properties of hybridsbetween
Salmonella phage P22 and coliphage lambda. Nature 251:584-589.
Strathern A. and I. Herskowitz (1975). Defective prophage in Escherichia
coli K12 strains. Virology 67:136-143.
Eisen H., M. Georgiou, C.P. Georgopoulos, G. Gussin and I. Herskowitz
(1975). The role of gene cro in phage development. Virology
68:266-269.
Hicks J.B. and I. Herskowitz (1976). Evidence for a new diffusible
element of mating pheromones in yeast. Nature 260:246-248.
Hicks J.B. and I. Herskowitz (1976). Interconversion of yeast mating
types. I. Direct observations of the action of the homothallism
(HO) gene. Genetics 83:245-258.
Hicks J.B. and I. Herskowitz (1977). Interconversion of yeast mating
types. II. Restoration of mating ability to sterile mutants in homothallic
and heterothallic strains. Genetics 85:373-393.
Hicks J.B., J.N. Strathern and I. Herskowitz (1977). Interconversion
of yeast mating types. III. Action of the homothallism (HO) gene
in cells homozygous for the mating type locus. Genetics 85:395-405.
Hicks J.B., J.N. Strathern and I. Herskowitz (1977). The cassette
model of mating type interconversion. In: DNA Insertion Elements
Plasmids and Episomes, A. Bukhari J. Shapiro and S. Adhya, eds. Cold Spring
Harbor Laboratory, Cold Spring Harbor, NY, pp. 457-462.
Herskowitz I. (1977). Mating type interconversion in yeast and its
relationship to development in higher eukaryotes. In: Proceedings
of the 1977 ICN UCLA Symposium: Molecular Approaches to Eukaryotic Genetic
Systems, G. Wilcox J. Abelson and C.F. Fox, eds. Academic Press, NY, pp.
193-202.
Jones M.O. and I. Herskowitz (1978). Mutants of bacteriophage lambda
which do not require the cIII gene for efficient lysogenization.
Virology 88:199-212.
Jones M.O., R. Fischer I. Herskowitz and H. Echols (1979). Location
of the regulatory site for establishment of repression by bacteriophage
lambda. Proc. Natl. Acad. Sci. USA 76:150-154.
Strathern J.N. and I. Herskowitz (1979). Asymmetry and directionality
in production of new cell types during clonal growth: The switching
pattern of homothallic yeast. Cell 17:371-381.
McCullough J. and I. Herskowitz (1979). Mating pheromones of Saccharomyces
kluyveri: Pheromone interactions between S. kluyveri and
S. cerevisiae. J. Bacteriol. 138:146-154.
Blair L.C., P.J. Kushner and I. Herskowitz (1979). Mutations of
HMa and HMa loci and their bearing on the cassette model
of mating type interconversion in yeast. In: Eukaryotic Gene Regulation,
ICN UCLA Symposium on Molecular and Cellular Biology, Vol. 14, T. Maniatis
and R. Axel, eds. Academic Press, NY, pp. 13-26.
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Strathern J.N., L.C. Blair and I. Herskowitz (1979). Healing of
mat mutations and control of mating type interconversion by the
mating type locusin Saccharomyces cerevisiae. Proc. Natl.
Acad. Sci. USA 76:3425-3429.
Kushner P.J., L.C. Blair and I. Herskowitz (1979). Control of yeast
cell types by mobile genes--a test. Proc. Natl. Acad. Sci. USA 76:5264-5268.
Strathern J.N., C.S. Newlon, I. Herskowitz and J.B. Hicks (1979).
Isolation of a circular derivative of yeast chromosome III: Implications
for the mechanism of mating type interconversion. Cell 18:309-319.
Rine J., J.N. Strathern, J.B. Hicks and I. Herskowitz (1979). A
suppressor of mating type locus mutations in Saccharomyces cerevisiae:
Evidence for and identification of cryptic mating type loci. Genetics
93:877-901.
Toothman P.J. and I. Herskowitz (1980). Rex dependent exclusion
of lambdoid phages. I. Prophage requirements for exclusion.
Virology 102:133-146.
Toothman P.J. and I. Herskowitz (1980). Rex dependent exclusion
of lambdoid phages. II. Determinants of sensitivity to exclusion.
Virology 102:147-160.
Toothman P.J. and I. Herskowitz (1980). Rex dependent exclusion
of lambdoid phages. III. Physiology of the abortive infection.
Virology 102:161-171.
Herskowitz I., L. Blair, D. Forbes, J. Hicks, Y. Kassir, P. Kushne,r J.
Rine, G. Sprague Jr. and J. Strathern (1980). Control of cell types
in Saccharomyces cerevisiae and a hypothesis for development
in higher eukaryotes. In: The Molecular Genetics of Development,
W. Loomis and T. Leighton, eds. Academic Press, NY, pp. 79-118.
Herskowitz I., J. Rine, G. Sprague Jr. and R. Jensen (1980). Control
of cell type in yeast by genetic cassettes. In: Miami Winter
Symposium 17: Mobilization and Reassembly of Genetic Information.
W.A. Scott R. Werner J. Schultz and D.R. Joseph, eds. Academic Press,
NY, pp. 133-151.
Rine J. and I. Herskowitz (1980). The trans action of HMRa
in mating type interconversion. Mol. Gen. Genet. 180:99-105.
Kassir Y. and I. Herskowitz (1980). A dominant mutation (SAD) bypassing
the requirement for the a mating type locus in yeast
sporulation. Mol. Gen. Genet. 180:315-322.
Herskowitz I. and D. Hagen (1980). The lysis lysogeny decision of
bacteriophage lambda: Explicit programming and responsiveness.
Ann. Rev. Genetics 14:399-445.
Sprague
Jr. G., J. Rine and I. Herskowitz (1981). Homology and nonhomology
at the mating type locus of yeast. Nature 289:250-252.
Rine J., R. Jensen, D. Hagen, L. Blair and I. Herskowitz (1981).
The pattern of switching and the fate of the replaced cassette in yeast
mating type interconversion. Cold Spring Harbor Symp. Quant. Biol.
45:951-960.
Strathern J., J. Hicks and I. Herskowitz (1981). Control of cell
type in yeast by the mating type locus: The a1a2
hypothesis. J. Mol. Biol. 147:357-372.
Sprague Jr. G. and I. Herskowitz (1981). Control of yeast cell type
by the mating type locus. I. Identification and control of expression
of the a-specific gene BAR1. J. Mol. Biol.
153:305-321.
Sprague Jr. G., J. Rine and I. Herskowitz (1981). Control of yeast
cell type by the mating type locus. II. Genetic interactions between
MATa and unlinked a-specific
STE genes. J. Mol. Biol. 153:323-335.
Rine J., G. Sprague Jr. and I. Herskowitz (1981). The rme1
mutation of Saccharomyces cerevisiae: Map position and
bypass of mating type locus control of sporulation. Mol. Cell. Biol.
1:958-960.
Herskowitz I. (1981). Genetic interactions among yeast cassettes.
In: Molecular Genetics in Yeast, D. von Wettstein J. Friis M. Keilland
Brandt and A. Stenderup, eds. Alfred Benzon Symp. 16; Munksgaard Press,
Copenhagen, pp. 103-118.
Herskowitz I. and Y. Oshima (1981). Control of cell type in Saccharomyces
cerevisiae: Mating type and mating type interconversion.
In: The Molecular Biology of the Yeast Saccharomyces: Life
Cycle and Inheritance., Strathern J.N., E.W. Jones and J.R. Broach,
eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp.
181-209.
Forbes D. and I. Herskowitz (1982). Polarity suppression by the
Q gene product of bacteriophage lambda. J. Mol. Biol. 160:549-569.
Kurjan J. and I. Herskowitz (1982). Structure of a yeast pheromone
gene (MF): A putative a-factor precursor contains four
tandem copies of a-factor. Cell 30:933-943.
Herskowitz I. (1982). The MATa2
gene. Rec. Adv. Yeast Mol. Biol. 1:320-331.
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Sprague Jr. G.F., R. Jensen and I. Herskowitz (1983). Control of
yeast cell type by the mating type locus: Positive regulation of
the a specific STE3 gene by the MATa1
product. Cell 32:409-415.
Jensen R., G. Sprague Jr. and I. Herskowitz (1983). Regulation of
yeast mating type interconversion: Feedback control of HO
gene expression by the yeast mating type locus. Proc. Natl. Acad.
Sci. USA 80:3035-3039.
Kassir Y., J.B. Hicks and I. Herskowitz (1983). SAD mutation
of yeast is an extra a cassette. Mol. Cell.
Biol. 3:871-880.
Herskowitz I. (1983). Cellular differentiation cell lineages and
transposable genetic cassettes in yeast. Curr. Top. Dev. Biol. 18:1-14.
Herskowitz I. (1983). Determination of yeast cell type. Symp. Soc.
Dev. Biol. 41:65-75.
Herskowitz I., S. Roark and E. Lynch (1983). Lambda (ThePoster).
In: Bacteriophage Lambda. II, Weisberg R., F.W. Stahl and J.W. Roberts,
eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Hall M.N., L. Hereford
and I. Herskowitz (1984). Targeting of E. coli beta galactosidase
to the nucleus in yeast. Cell 36:1057-1065.
Friedman D.I., E.R. Olson, C. Georgopoulos, K. Tilly, I. Herskowitz and
F. Banuett (1984). Interactions of bacteriophage and host macromolecules
in the growth of bacteriophage lambda. Microbiol. Rev. 48:299-325.
Stern M., R. Jensen and I. Herskowitz (1984). Five SWI
genes are required for expression of the HO gene in yeast.
J. Mol. Biol. 178:853-868.
Herskowitz I. and F. Banuett (1984). Interaction of phage host and
environmental factors in governing the lambda lysis-lysogeny decision.
Proceedings of the XV International Congress of Genetics (New Delhi 1983)
Oxford and IBH Publishing Co., New Delhi, pp. 59-73.
Wilson K.L. and I. Herskowitz (1984). Negative regulation of STE6
gene expression by the a2 product of yeast.
Mol. Cell. Biol. 4:2420-2427.
Jensen R.E. and I. Herskowitz (1984). Directionality and regulation
of cassette substitution in yeast. Cold Spring Harbor Symp. Quant.
Biol. 49:97-104.
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Simon M. and I. Herskowitz (1985). Introduction. In: Genome
Rearrangement UCLA Symposia on Molecular and Cellular Biology Vol. 20
M. Simon and I. Herskowitz eds. Alan Liss Inc. New York xv-xix.
Johnson A.D. and I. Herskowitz (1985). A repressor (MATa2
product) and its operator control expression of a set of cell type specific
genes inyeast. Cell 42:237-247.
Fields S. and I. Herskowitz (1985). The yeast STE12 product
is required for expression of two sets of cell-type-specific genes.
Cell 42:923-930.
Herskowitz I. (1985). Yeast as the universal cell (News andViews).
Nature 316:678-679.
Herskowitz I. (1985). Master regulatory loci in yeast and lambda.
Cold Spring Harbor Symp. Quant. Biol. 50:565-574.
Herskowitz I. (1986). Cell type determination and mating type interconversion
in yeast. In: Cellular and Molecular Aspects of Developmental Biology
Fougereau M. and R. Stora eds. Les Houches XLII 67-98.
Banuett F., M.A. Hoyt, L. McFarlane, H. Echols and I. Herskowitz (1986).
hflB a new Escherichia coli locus regulating lysogeny
and the level of bacteriophage lambda cII protein. J. Mol. Biol.
187:213-224.
Mitchell A.P. and I. Herskowitz (1986). Activation of meiosis and
sporulation by repression of the RME1 product in yeast.
Nature 319:738-742.
Wilson K.L. and I. Herskowitz (1986). Sequences upstream of the
STE6 gene required for its expression and regulation by the mating
type locus in Saccharomyces cerevisiae. Proc. Natl. Acad.
Sci. USA 83:2536-2540.
Herskowitz I. (1986). Specialized cell types in yeast: Their
use in addressing problems in cell biology. In: Yeast Cell Biology
Hicks J.B. ed. UCLA Symposia on Molecular and Cellular Biology Alan R.
Liss Inc. New York 625-656.
Russell D.W., R. Jensen, M.J. Zoller, J. Burke, B. Errede, M. Smith and
I. Herskowitz (1986). Structure of the Saccharomyces cerevisiae
HO gene and analysis of its upstream region. Mol. Cell. Biol.
6:4281-4294.
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Powers S., S. Michaelis, D. Broek, S. Santa-Anna A., J. Field, I. Herskowitz
and M. Wigler (1987). RAM, a gene of yeast required for
a functional modification of RAS proteins and mating pheromone a-factor.
Cell 47:413-422.
Sternberg P.W., M.J. Stern, I. Clark and I. Herskowitz (1987). Activation
of the yeast HO gene by release from multiple negative controls.
Cell 48: 567-577.
Herskowitz I. (1987). A master regulatory locus that determines
cell specialization in yeast. The Harvey Lectures 81:67-92.
Rine J. and I. Herskowitz (1987). Four genes responsible for a position
effect on expression from HML and HMR in Saccharomyces
cerevisiae. Genetics 116:9-22.
Herskowitz I. (1987). Functional inactivation of genes by dominant
negative mutations. Nature 329:219-222.
Wilson K.L. and I. Herskowitz (1987). STE16, a new gene
required for pheromone production by a cells
of Saccharomyces cerevisiae. Genetics 115: 441-449.
Banuett F. and I. Herskowitz (1987). Identification of polypeptides
encoded by an Escherichia coli locus (hflA) that governs
the lysis lysogeny decision of bacteriophage lambda. J. Bacteriol.
169:4076-4085.
Herskowitz I. and L. Marsh (1987). Conservation of a receptor/signal transduction
system. Cell 50:995-996.
Fields S. and I. Herskowitz (1987). Regulation by the yeast mating
type locus of STE12, a gene required for cell type specific expression.
Mol. Cell. Biol. 7:3818-3821.
Michaelis S. and I. Herskowitz (1988). The a-factor
pheromone of Saccharomyces cerevisiae is essential for mating.
Mol. Cell. Biol. 8:1309-1318.
Banuett F. and I. Herskowitz (1988). Ustilago maydis smut
of maize. In: Genetics of Phytopathogenic Fungi G.S. Sidhu ed. Advances
in Plant Pathology 6 Academic Press London 427-455.
Marsh L. and I. Herskowitz (1988). STE2 protein of Saccharomyces
kluyveri is a member of the rhodopsin/beta adrenergic receptor family
and is responsible for recognition of the peptide ligand a factor.
Proc. Natl. Acad. Sci. USA 85:3855-3859.
Herskowitz I. (1988). The Hawthorne deletion twenty five years later.
Genetics 120:857-861.
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Herskowitz I. (1988). The life cycle of the budding yeast Saccharomyces
cerevisiae. Microbiol. Rev. 52:536-553.
Marsh L. and I. Herskowitz (1988). From membrane to nucleus: The
pathway of signal transduction in yeast and its genetic control.
Cold Spring Harbor Symp. Quant. Biol. 53:557-565.
Andrews B.J. and I. Herskowitz (1989). Identification of a DNA binding
factor involved in cell cycle control of the yeast HO gene.
Cell 57:21-29.
Banuett F. and I. Herskowitz (1989). Different a alleles
of Ustilago maydis are necessary for maintenance of filamentous
growth but not for meiosis. Proc. Natl. Acad. Sci. USA 86:5878-5882.
Herskowitz I. (1989). Negative growth factors in yeast: Genetic
control of synthesis and response. In: The Regulation of Proliferation
and Differentiation in Normal and Neoplastic Cells, E. Frei III, ed. Academic
Press Inc., NY, pp. 21-37.
Herskowitz I. (1989). Multiple loci for resistance to negative growth
factors in yeast. In: Current Communications in Molecular Biology:
Recessive Oncogenes and Tumor Suppression, W. Cavenee N. Hastie and E.
Stanbridge, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor,
NY, pp. 221-234.
Herskowitz I. (1989). A regulatory hierarchy for cell specialization
in yeast. Nature 342:749-757.
Andrews B.J. and I. Herskowitz (1989). The yeast SWI4 protein contains
a motif present in developmental regulators and is part of a complex involved
in cell-cycle-dependent transcription. Nature 342:830-833.
Schulz B,. F. Banuett, M. Dah,l R. Schlesinger, W. Schaefer, T. Martin,
I. Herskowitz and R. Kahmann (1990). The b alleles of U.
maydis whose combinations program pathogenic development code for
polypeptides containing a homeodomain related motif. Cell 60:295-306.
Neiman A.M., F. Chang, K. Komachi and I. Herskowitz (1990). CDC36
and CDC39 are negative elements in the signal transduction pathway
of yeast. Cell Regulation 1:391-401.
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Herskowitz I. and R.E. Jensen (1990). Putting the HO gene
to work: practical uses for mating
type switching. Meth. Enzymol. 194:132-146.
Andrews B.J. and I. Herskowitz (1990). Regulation of cell-cycle-dependent
gene expression in yeast. J. Biol. Chem. 265:14057-14060.
Wang H., I. Clar,k P.R. Nicholson, I. Herskowitz and D.J. Stillman (1990).
The Saccharomyces cerevisiae SIN3 gene, a negative regulator
of HO, contains four paired amphipathic helix motifs. Mol.
Cell. Biol. 10:5927-5936.
Chang F. and I. Herskowitz (1990). Identification of a gene necessary
for cell cycle arrest by a negative growth factor of yeast: FAR1 is an
inhibitor of a G1 cyclin CLN2. Cell 63:999-1011.
Brenner S., W. Dove, I. Herskowitz and R. Thomas (1990). Genes and
development: molecular and logical themes. Genetics 126:479-486.
Peterson C.L., W. Kruger and I. Herskowitz (1991). A functional
interaction between the C-terminal domain of RNA polymerase II and the
negative regulator SIN1. Cell 64:1135-1143.
Kruger W. and I. Herskowitz (1991). A negative regulator of HO
transcription SIN1 (SPT2) is a nonspecific DNA-binding protein related
to HMG1. Mol. Cell. Biol. 11:4135-4146.
Chant J. and I. Herskowitz (1991). Genetic control of bud site selection
in yeast by a set of gene products that constitute a morphogenetic pathway.
Cell 65:1203-1212.
Chant J., K. Corrado, J.R. Pringle and I. Herskowitz (1991). Yeast
BUD5, encoding a putative GDP GTP exchange factor, is necessary
for bud site selection and interacts with bud formation gene BEM1.
Cell 65:1213-1224.
Marsh L., A.M. Neiman and I. Herskowitz (1991). Signal transduction
during pheromone response in yeast. Ann. Rev. Cell Biol. 7:699-72
Ogas J., B.J. Andrews and I. Herskowitz (1991). Transcriptional
activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26)
by SWI4, a positive regulator of G1-specific transcription. Cell
66:1015-1026.
Covitz P.A., I. Herskowitz and A.P. Mitchell (1991). The yeast RME1
gene encodes a putative zinc finger protein that is directly repressed
by a1-a2. Genes Dev.
5:1982-1989.
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Herskowitz I. and F. Chang (1991). Arrest of the yeast cell cycle
by a negative growth factor: antagonism of a G1 cyclin (CLN2) by FAR1.
In: Origins of Human Cancer: A Comprehensive Review, J. Brugge, T. Curran,
E. Harlow and F. McCormick, eds. Cold Spring Harbor Laboratory Press,
Cold Spring Harbor, NY, pp. 35-43.
Herskowitz I., J. Ogas, B.J. Andrews and F. Chang (1991). Regulators
of synthesis and activity of the G1 cyclins of budding yeast. Cold
Spring Harbor Symp. Quant. Biol. 56:33-40.
Horvitz H.R. and I. Herskowitz (1992). Mechanisms of asymmetric
cell division: two Bs or not two Bs, that is the question. Cell
68:1-20.
Peterson C.L. and I. Herskowitz (1992). Characterization of theyeast
SWI1, SWI2 and SWI3 genes, which encode a global activator
of transcription. Cell 68:573-583.
Chenevert J., K. Corrado, A. Bender, J. Pringle and I. Herskowitz (1992).
A yeast gene (BEM1) whose product contains two SH3 domains.
Nature 356:77-79.
Chang F. and I. Herskowitz (1992). Phosphorylation of FAR1 in response
to a-factor: a possible requirement for cell cycle arrest. Mol.
Cell Biol. 3:445-450.
Herskowitz I. (1992). Yeast branches out. Nature 357:190-191.
Herskowitz I. (1992). Controlling elements mutable alleles and matin-
type interconversion. In: The Dynamic Genome: Barbara McClintock's
Ideas in the Century of Genetics, N. Federoff and D. Botstein, eds., Cold
Spring Harbor Laboratory Press, Cold Spring Harbor New York, pp. 289-297.
Hoffman F.M., P.W. Sternberg and I. Herskowitz (1992). Learning
about cancer genes through invertebrate genetics. Curr. Opin. Genet.
Dev. 2:45-52.
Lee R.T., C.L. Peterson, A.F. Calman, I. Herskowitz and J.J. O'Donnell
(1992). Cloning of a human galactokinase gene (GK2) on
chromosome 15 by complementation in yeast. Proc. Natl. Acad. Sci.
USA 89:10887-10891.
Yoshinaga S.K., C.L. Peterson, I. Herskowitz and K.R. Yamamoto (1992).
Roles of the SWI1, SWI2 and SWI3 proteins for transcriptional enhancement
by steroid receptors. Science 258:1598-1604.
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Neiman A.M., B.J. Stevenson, H. P. Xu, G.F. Sprague Jr., I. Herskowitz,
M. Wigler and S. Marcus (1992). Functional homology of protein kinases
required for sexual differentiation in Schizosaccharomyces pombe
and Saccharomyces cerevisiae suggests a conserved signal transduction
module in eukaryotic organisms. Mol. Biol. Cell 4: 107-120.
Herskowitz I., J. Rine and J. Strathern. 1992. Mating type determination
and mating-type interconversion in Saccharomyces cerevisiae.
In: The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene
Expression, E.W. Jones, J.R. Pringle and J.R. Broach, eds. Cold Spring
Harbor Laboratory Press, Cold Spring Harbor, NYk, pp. 583-656.
Herskowitz I., B. Andrews, W. Kruger, J. Ogas, A. Sil, C. Coburn and C.
Peterson. Integration of multiple regulatory inputs in the control
of HO expression in yeast. 1992. In: Transcriptional
Regulation, S.L. McKnight and K.R. Yamamoto, eds. Cold Spring Harbor Laboratory
Press, Cold Spring Harbor, NY, pp. 949-974.
McElreavey K., E. Vilain, N. Abbas, I. Herskowitz and M. Fellous (1993).
A regulatory cascade hypothesis for mammalian sex determination: SRY represses
a negative regulator of male development. Proc. Natl Acad. Sci.
USA 90: 3368-3372.
Peter M., A. Gartner, J. Horecka, G. Ammerer and I. Herskowitz (1993).
FAR1 protein links the signalling pathway to the cell cycle machinery
in yeast. Cell 73:747-760.365:269-274.
Park H.-O., J. Chant and I. Herskowitz (1993). BUD2 encodes a
GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site
selection in yeast. Nature 365:269-274.
Noble J.A., M.A. Innis, E.V. Koonin, K.E. Rudd, F. Banuett and I. Herskowitz
(1993). The Escherichia coli hflA locus encodes a putative
GTP-binding protein and two membrane proteins, one of which contains a
protease like domain. Proc. Natl. Acad. Sci. USA 90:10866-10870.
Li J.J. and I. Herskowitz (1993). Isolation of ORC6, a
component of the yeast origin recognition complex by a one hybrid system.
Science 262:1870-1874.
Herskowitz J., J. Cuddihy and I. Herskowitz (1993). Double Talking Helix
Blues (children's book). Cold Spring Harbor Laboratory Press, Plainview,
NY.
Chenevert J., N. Valtz and I. Herskowitz (1994). Identification
of genes required for normal pheromone-induced cell polarization in Saccharomyces
cerevisiae. Genetics 136: 1287-1296.
Kaffman A., I. Herskowitz, R. Tjian and E.K. O’Shea (1994).
Phosphorylation of the transcription factor PHO4 by a cyclin CDK complex,
PHO80-PHO85. Science 263:1153-1156.
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Neiman A.M. and I. Herskowitz (1994). Reconstitution of a yeast
protein kinase cascade in vitro: activation of the yeast MEK
homologue STE7 by STE11. Proc. Natl. Acad. Sci. USA 91:3398-3402.
Banuett F. and I Herskowitz (1994). Identification of Fuz7, a Ustilago
maydis MEK/MAPKK homolog required for a-Locus-dependent
an- independent steps in the fungal life cycle. Genes Dev. 8:1367-1378.
Banuett F. and I. Herskowitz (1994). Morphological transitions in
the life cycle of Ustilago maydis and their genetic control by
the a and b loci. Exper. Mycol. 18:247-266.
Peter M. and I. Herskowitz (1994). Direct inhibition of the yeast
cyclin dependent kinase Cdc28-Cln by Far1. Science 265:1228-1231.
Santa Anna-Arriola S. and I. Herskowitz (1994). Isolation and DNA
sequence of the STE13 gene encoding dipeptidyl aminopeptidase.
Yeast 10:801-810.
Peter M. and I. Herskowtiz (1994). Joining the complex: cyclin-dependent
kinase inhibitory proteins and the cell cycle. Cell 79:181-184.
Espinoza F.H., J. Ogas, I. Herskowitz and D.O. Morgan (1994). Cell
cycle control by a complex of the cyclin HCs26 (PCL1) and the kinase PHO85.
Science 266:1388-1391.
Gerber M.R., A. Farrell, R.J. Deshaies, I. Herskowitz and D.O. Morgan
(1995). Cdc37 is required for association of the protein kinase Cdc28
with G1 and mitotic cyclins. Proc. Natl. Acad. Sci. USA 92:4651-4655.
Herskowitz I. (1995). MAP kinase pathways in yeast: for mating and more.
Cell 80:187-197.
Chant J., M. Mischke, E. Mitchell, I. Herskowitz and J.R. Pringle (1995).
Role of Bud3p in producing the axial budding pattern of yeast. J.
Cell Biol. 129:767-778.
Valtz N., M. Peter and I Herskowitz (1995). FAR1 is required
for oriented polarization of yeast cells in response to mating pheromones.
J. Cell Biol. 131:863-873.
Kruger W. ,C.L. Peterson, A. Sil, C. Coburn, G. Arents, E.N. Moudrianakis
and I. Herskowitz (1995). Amino acid substitutions in the structured domains
of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF
complex for transcription. Genes Dev. 9:2770-2779.
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Herskowitz I., H.-O. Park, S. Sanders, N. Valtz and M. Peter (1995). Programming
of cell polarity in budding yeast by endogenous and exogenous signals.
Cold Spring Harbor Symp. Quant. Biol. 60:717-727.
Sil A. and I. Herskowitz (1996). Identification of an asymmetrically localized
determinant required for lineage specific transcription of the yeast HO
gene. Cell 84:711-722.
Banuett F. and I Herskowitz (1996). Discrete developmental stages during
teliospore formation in the corn smut fungus Ustilago maydis.
Development 122:2965-2976.
Sanders S.L. and I. Herskowitz (1996). The Bud4 protein of yeast required
for axial budding is localized to the mother/budneck in a cell cycle dependent
manner. J. Cell Biol. 134:413-427.
Valtz N. and I. Herskowitz (1996). Pea2 protein of yeast is localized
to sites of polarized growth and is required for efficient mating and
bipolar budding. J. Cell Biol. 135:725-739.
Peter M., A.M. Neiman, H.-O. Park, M. van Lohuizen and I. Herskowitz (1996).
Functional analysis of the interaction between the small GTP binding protein
Cdc42 and the Ste20 protein kinase in yeast. EMBO J. 15:7046-7059.
Leberer E., J. Chenevert, T. Leeuw, D. Harcus, I. Herskowitz and D.Y.
Thomas (1996). Genetic interactions indicate a role for Mdg1p and the
SH3 domain protein Bem1p in linking the G-protein mediated pheromone signaling
pathway to regulators of cell polarity. Mol. Gen. Genet. 252:608-621.
Park H.-O., E. Bi, J.R. Pringle and I. Herskowitz. (1997). Two active
states of the Ras related Bud1/Rsr1 protein bind to different effectors
to determine yeast cell polarity. Proc. Natl. Acad. Sci. USA 94:4463-4468.
Gray J.V., J.P Ogas, Y. Kamada, M. Stone, D.E. Levin and I. Herskowitz
(1997). A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae
in bud emergence and identification of a putative upstream regulator.
EMBO J. 16:4924-4937.
Philips J. and I. Herskowitz (1997). Osmotic balance regulates cell fusion
during mating in Saccharomyces cerevisiae. J. Cell Biol. 138:961-974.
Takizawa P.A., A. Sil, J.R. Swedlow, I. Herskowitz and R.D. Vale (1997).
Actin dependent localization of an RNA encoding a cell-fate determinant
in yeast. Nature 389:90-93.
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Henchoz S., Y. Chi, B. Catarin, I. Herskowitz, R.J. Deshaies and M. Peter
(1997). Phosphorylation and ubiquiti- dependent degradation of the cyclin-dependent
kinase inhibitor Far1p in budding yeast. Genes Dev. 11:3046-3060.
Herskowitz I. (1997). Building organs and organisms: elements of morphogenesis
exhibited by budding yeast. Cold Spring Harbor Symp. Quant. Biol. 62:57-63.
Shaham S., M.A. Shuman and I. Herskowitz (1998) Death-defying yeast identify
novel apoptosis genes. Cell 92:425-427.
Herskowitz I. and F. W. Stahl (1998). Genes to Cells in Mishima:
meeting report. Genes to Cells 3:1-8.
Chu S. and I. Herskowitz (1998). Gametogenesis in yeast is regulated
by a transcriptional cascade dependent on Ndt80. Mol. Cell 1:685-696.
Tabtiang R. and I. Herskowitz (1998). Nuclear proteins Nut1p and Nut2p
cooperate to negatively regulate a Swi4p dependent lacZ reporter
gene in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:4707-4718.
O’Rourke S. and I. Herskowitz (1998) The Hog1 MAPK prevents cross
talk between the HOG and pheromone response MAPK pathways in S. cerevisiae.
Genes Dev. 12:2874-2886.
Chu S., J. DeRisi, M. Eisen, J. Mulholland, D. Botstein, P.O. Brown and
I. Herskowitz (1998). The transcriptional program of sporulation in budding
yeast. Science 282:699-705.
Philips J. and I. Herskowitz (1998) Identification of Kel1p, a Kelch domain-containing
protein involved in cell fusion and morphology in Saccharomyces
cerevisiae. J. Cell Biol. 143:375-389.
Herskowitz I. (1998). Coming early to the late genes. Curr. Biol. 8:R827-R828.
Butty A.C., P.M. Pryciak, L.S. Huan,g I. Herskowitz and M. Peter (1998).
The role of Far1p in linking the heterotrimeric G protein to polarity
establishment proteins during yeast mating. Science 282:1511-1516.
Sanders S.L., M. Gentzsch, W. Tanner and I. Herskowitz (1999). O-glycosylation
of AxI1/Bud1Op by Pmt4p is required for its stability, localization and
function in daughter cells. J. Cell Biol 145:1177-1188.
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Park H.-O., A. Sanson and I. Herskowitz (1999). Localization of Bud2 protein
a GTPase activating protein necessary for programming cell polarity in
yeast to the presumptive bud site. Genes Dev. 13:1912-1917.
Grether M. and I. Herskowitz (1999) Genetic and biochemical characterization
of the yeast Spo12 protein. Mol. Biol. Cell 10:3689-3703.
Schlumpberger M., H. Wille, M.A. Baldwin, D.A. Butler, I. Herskowitz and
S. B. Prusiner (2000). The prion domain of yeast Ure2p induces autocatalytic
formation of amyloid fibers by a recombinant fusion protein. Protein
Sci. 9:1-12.
O'Shea E.K. and I. Herskowitz (2000) The ins and outs of cell polarity
decisions. Nat. Cell Biol. 2:E39-E40.
Maxon M.E. and I. Herskowitz (2001) Ash1p is a site specific DNA binding
protein that actively represses transcription. Proc. Natl. Acad. Sci.
USA 98:1495-1500.
Tadauchi T., K. Matsumoto, I. Herskowitz and K. Irie (2001). Post
Transcriptional Regulation of HO Through the HO 3’
UTR by Mpt5, a Yeast Homolog of Pumilio and FBF. EMBO J. 20:552-561.
Schlumpberger M.S.B., S.B. Prusiner and I. Herskowitz (2001). The prion
domain of yeast Ure2p induces autocatalytic formation of amyloid fibers
by a recombinant fusion protein. Protein Science 9:1-12.
Schlumpberger M S.B. Prusiner and I. Herskowitz (2001). Induction of distinct
[URE3] yeast prion strains. Mol. Cell. Biol. 21:7035-7046.
Herskowitz I. (2001) Cassette Model. In: Encyclopedia of Genetics,
Brenner S. and Miller J.H., eds. Academic Press, New York, NY, pp. 275-278.
O’Rourke S.M. and I. Herskowitz (2002). A third osmosensing
branch in Saccharomyces cerevisiae requires the Msb2 protein
and functions in parallel to the Sho1 branch. Mol. Cell. Biol. 22:4739-4749.
Irie K., T. Tadauch,i P.A. Takizawa, R.D. Vale, K. Matsumoto and I. Herskowitz
(2002). The Khd1 protein, which has three KH RNA-binding motifs,
is required for proper localization of ASH1 mRNA in yeast. EMBO
J. 21:1158-1167.
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McBride H.J., A. Sil, V. Measday, Y. Yu, J. Moffat, M.E. Maxon, I. Herskowitz,
B. Andrews and D.J. Stillman (2001). The protein kinase Pho85 is
required for asymmetric accumulation of the Ash1 protein in Saccharomyces
cerevisiae. Mol. Microbiol. 42:345-353.
Herskowitz I. and E. O’Shea (2002). The 2001 Thomas Hunt Morgan
Medal. Yasuji Oshima. Genetics 160:367-368.
Herskowitz I. (2002). Regulating natural health products (letter).
Science 296:46-47.
O'Rourke S.M., I. Herskowitz and E.K. O'Shea (2002). Yeast go the
whole HOG for the hyperosmotic response. Trends Genet. 18:405-12.
Leabman M.K., C.C. Huang, M. Kawamoto, S.J. Johns, D. Stryke, T.E. Ferrin,
J. DeYoung, T. Taylor, A.G. Clark, I. Herskowitz and K.M. Giacomini (2002).
Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit
altered function. Pharmacogenetics 12:395-405.
Ishida S., J. Lee, D.J. Thiele and I. Herskowitz (2002). Uptake
of the anticancer drug cisplatin mediated by the copper transporter, Ctr1,
in yeast and mammals. Proc. Natl. Acad. Sci. USA 99:14298-302.
Banuett F. and I. Herskowitz (2002). Bud morphogenesis and the actin
and microtubule cytoskeletons during budding in the corn smut fungus Ustilago
maydis. Fungal Genet. Biol. 37:149-70.
Stryke D., C.C. Huang, M. Kawamoto, S.J. Johns, E.J. Carlson, J.A. Deyoung,
M.K. Leabman, I. Herskowitz, K.M. Giacomini and T.E. Ferrin (2003).
SNP analysis and presentation in the Pharmacogenetics of Membrane Transporters
Project. Pac. Symp. Biocomput. 535-47.
Clyne R.K., V.L. Katis, L. Jessop, K.R. Benjamin, I. Herskowitz, M. Lichten
and K. Nasmyth (2003). Polo-like kinase Cdc5 promotes chiasmata
formation and cosegregation of sister centromeres at meiosis I.
Nat. Cell Biol. 5:480-5.
Leabman M.K., C.C. Huang, J. DeYoung, E.J. Carlson, T.R. Taylor,
M. De La Cruz, S.J. Johns, D. Stryke, M. Kawamoto, T.J. Urban, D.L. Kroetz,
T.E. Ferrin, A.G. Clark, N. Risc,h I. Herskowitz, K.M. Giacomini and Pharmacogenetics
of Membrane Transporters Investigators (2003). Natural variation
in human membrane transporter genes reveals evolutionary and functional
constraints. Proc. Natl. Acad. Sci. USA 100:5896-5901.
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Shu Y., M.K. Leabman, B. Feng, L.M. Mangravite, C.C. Huang, D. Stryke,
M. Kawamoto, S.J. Johns, J. DeYoung, E. Carlson, T.E. Ferrin, I.
Herskowitz, K.M. Giacomini and Pharmacogenetics of Membrane Transporters
Investigators (2003). Evolutionary conservation predicts function
of variants of the human organic cation transporter, OCT1. Proc.
Natl. Acad. Sci. USA 100:5902-5907.
Osato D.H., C.C. Huang, M. Kawamoto, S.J. Johns, D. Stryke, J. Wang, T.E.
Ferrin, I. Herskowitz and K.M. Giacomini (2003). Functional
characterization in yeast of genetic variants in the human equilibrative
nucleoside transporter, ENT1. Pharmacogenetics 13:297-301.
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