Herskowitz Full Bibliography (182 pubs, chronological)

Herskowitz I. and E. R. Signer (1970). A site essential for expression of all late genes in bacteriophage lambda. J. Mol. Biol. 47:545-556.

Herskowitz I. and E.R. Signer (1970).  Control of transcription from the r strand of bacteriophage lambda.  Cold Spring Harbor Symp. Quant. Biol. 35:355-368.
 
Georgopoulos C.P. and I. Herskowitz (1971).  Escherichia coli mutants blocked in lambda DNA synthesis.  In:  The Bacteriophage Lambda A.D. Hershey ed. Cold Spring Harbor Laboratory Press Cold Spring Harbor NY pp. 553-564.
 
Herskowitz I. (1973).  Control of gene expression in bacteriophage lambda.  Ann. Rev. Genetics 7:289-324.
 
Herskowitz I. and E.R. Signer (1974).  Substitution mutations in bacteriophage lambda with new specificity for late gene expression.  Virology 61:112-119.
 
Botstein D. and I. Herskowitz (1974).  Properties of hybridsbetween Salmonella phage P22 and coliphage lambda.  Nature 251:584-589.
 
Strathern A. and I. Herskowitz (1975).  Defective prophage in Escherichia coli K12 strains.  Virology 67:136-143.
 
Eisen H., M. Georgiou, C.P. Georgopoulos, G. Gussin and I. Herskowitz (1975).  The role of gene cro in phage development.  Virology 68:266-269.
 
Hicks J.B. and I. Herskowitz (1976).  Evidence for a new diffusible element of mating pheromones in yeast.  Nature 260:246-248.

Hicks J.B. and I. Herskowitz (1976).  Interconversion of yeast mating types.  I. Direct observations of the action of the homothallism (HO) gene.  Genetics 83:245-258.

Hicks J.B. and I. Herskowitz (1977).  Interconversion of yeast mating types.  II. Restoration of mating ability to sterile mutants in homothallic and heterothallic strains.  Genetics 85:373-393.

Hicks J.B., J.N. Strathern and I. Herskowitz (1977).  Interconversion of yeast mating types.  III. Action of the homothallism (HO) gene in cells homozygous for the mating type locus.  Genetics 85:395-405.

Hicks J.B., J.N. Strathern and I. Herskowitz (1977).  The cassette model of mating type interconversion.  In: DNA Insertion Elements Plasmids and Episomes, A. Bukhari J. Shapiro and S. Adhya, eds. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 457-462.

Herskowitz I. (1977).  Mating type interconversion in yeast and its relationship to development in higher eukaryotes.  In: Proceedings of the 1977 ICN UCLA Symposium: Molecular Approaches to Eukaryotic Genetic Systems, G. Wilcox J. Abelson and C.F. Fox, eds. Academic Press, NY, pp. 193-202.

Jones M.O. and I. Herskowitz (1978).  Mutants of bacteriophage lambda which do not require the cIII gene for efficient lysogenization.  Virology 88:199-212.

Jones M.O., R. Fischer I. Herskowitz and H. Echols (1979).  Location of the regulatory site for establishment of repression by bacteriophage lambda.  Proc. Natl. Acad. Sci. USA 76:150-154.

Strathern J.N. and I. Herskowitz (1979).  Asymmetry and directionality in production of new cell types during clonal growth:  The switching pattern of homothallic yeast.  Cell 17:371-381.

McCullough J. and I. Herskowitz (1979).  Mating pheromones of Saccharomyces kluyveri: Pheromone interactions between S. kluyveri and S. cerevisiae.  J. Bacteriol. 138:146-154.

Blair L.C., P.J. Kushner and I. Herskowitz (1979).  Mutations of HMa and HMa loci and their bearing on the cassette model of mating type interconversion in yeast.  In: Eukaryotic Gene Regulation, ICN UCLA Symposium on Molecular and Cellular Biology, Vol. 14, T. Maniatis and R. Axel, eds. Academic Press, NY, pp. 13-26.

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Strathern J.N., L.C. Blair and I. Herskowitz (1979).  Healing of mat mutations and control of mating type interconversion by the mating type locusin Saccharomyces cerevisiae.  Proc. Natl. Acad. Sci. USA 76:3425-3429.

Kushner P.J., L.C. Blair and I. Herskowitz (1979).  Control of yeast cell types by mobile genes--a test.  Proc. Natl. Acad. Sci. USA 76:5264-5268.

Strathern J.N., C.S. Newlon, I. Herskowitz and J.B. Hicks (1979).  Isolation of a circular derivative of yeast chromosome III: Implications for the mechanism of mating type interconversion.  Cell 18:309-319.

Rine J., J.N. Strathern, J.B. Hicks and I. Herskowitz (1979).  A suppressor of mating type locus mutations in Saccharomyces cerevisiae:  Evidence for and identification of cryptic mating type loci.  Genetics 93:877-901.

Toothman P.J. and I. Herskowitz (1980).  Rex dependent exclusion of lambdoid phages.  I. Prophage requirements for exclusion.  Virology 102:133-146. 

Toothman P.J. and I. Herskowitz (1980).  Rex dependent exclusion of lambdoid phages.  II. Determinants of sensitivity to exclusion.  Virology 102:147-160.

Toothman P.J. and I. Herskowitz (1980).  Rex dependent exclusion of lambdoid phages.  III. Physiology of the abortive infection.  Virology 102:161-171.


Herskowitz I., L. Blair, D. Forbes, J. Hicks, Y. Kassir, P. Kushne,r J. Rine, G. Sprague Jr. and J. Strathern (1980).  Control of cell types in Saccharomyces cerevisiae and a hypothesis for development in higher eukaryotes.  In:  The Molecular Genetics of Development, W. Loomis and T. Leighton, eds. Academic Press, NY, pp. 79-118.

Herskowitz I., J. Rine, G. Sprague Jr. and R. Jensen (1980).  Control of cell type in yeast by genetic cassettes.  In:  Miami Winter Symposium 17: Mobilization and Reassembly of Genetic Information.  W.A. Scott R. Werner J. Schultz and D.R. Joseph, eds. Academic Press, NY, pp. 133-151.

Rine J. and I. Herskowitz (1980).  The trans action of HMRa in mating type interconversion.   Mol. Gen. Genet. 180:99-105.

Kassir Y. and I. Herskowitz (1980).  A dominant mutation (SAD) bypassing the requirement for the a mating type locus in yeast sporulation.  Mol. Gen. Genet. 180:315-322.

Herskowitz I. and D. Hagen (1980).  The lysis lysogeny decision of bacteriophage lambda:  Explicit programming and responsiveness.  Ann. Rev. Genetics 14:399-445.

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Sprague Jr. G., J. Rine and I. Herskowitz (1981).  Homology and nonhomology at the mating type locus of yeast.  Nature 289:250-252.

Rine J., R. Jensen, D. Hagen, L. Blair and I. Herskowitz (1981).  The pattern of switching and the fate of the replaced cassette in yeast mating type interconversion.  Cold Spring Harbor Symp. Quant. Biol. 45:951-960.

Strathern J., J. Hicks and I. Herskowitz (1981).  Control of cell type in yeast by the mating type locus:  The a1a2 hypothesis.  J. Mol. Biol. 147:357-372.

Sprague Jr. G. and I. Herskowitz (1981).  Control of yeast cell type by the mating type locus.  I. Identification and control of expression of the a-specific gene BAR1.  J. Mol. Biol. 153:305-321.

Sprague Jr. G., J. Rine and I. Herskowitz (1981).  Control of yeast cell type by the mating type locus.  II. Genetic interactions between MATa and unlinked a-specific STE genes.  J. Mol. Biol. 153:323-335. 

Rine J., G. Sprague Jr. and I. Herskowitz (1981).  The rme1 mutation of Saccharomyces cerevisiae:  Map position and bypass of mating type locus control of sporulation.  Mol. Cell. Biol. 1:958-960.

Herskowitz I. (1981). Genetic interactions among yeast cassettes.  In: Molecular Genetics in Yeast, D. von Wettstein J. Friis M. Keilland Brandt and A. Stenderup, eds. Alfred Benzon Symp. 16; Munksgaard Press, Copenhagen, pp. 103-118.

Herskowitz I. and Y. Oshima (1981).  Control of cell type in Saccharomyces cerevisiae:  Mating type and mating type interconversion.  In: The Molecular Biology of the Yeast Saccharomyces:  Life Cycle and Inheritance.,  Strathern J.N., E.W. Jones and J.R. Broach, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 181-209.

Forbes D. and I. Herskowitz (1982).  Polarity suppression by the Q gene product of bacteriophage lambda.  J. Mol. Biol. 160:549-569.

Kurjan J. and I. Herskowitz (1982).  Structure of a yeast pheromone gene (MF):  A putative a-factor precursor contains four tandem copies of a-factor.  Cell 30:933-943.

Herskowitz I. (1982).  The MATa2 gene.  Rec. Adv. Yeast Mol. Biol. 1:320-331.

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Sprague Jr. G.F., R. Jensen and I. Herskowitz (1983).  Control of yeast cell type by the mating type locus:  Positive regulation of the a specific STE3 gene by the MATa1 product.  Cell 32:409-415.

Jensen R., G. Sprague Jr. and I. Herskowitz (1983).  Regulation of yeast mating type interconversion:  Feedback control of HO gene expression by the yeast mating type locus.  Proc. Natl. Acad. Sci. USA 80:3035-3039.

Kassir Y., J.B. Hicks and I. Herskowitz (1983).  SAD mutation of yeast is an extra a cassette.  Mol. Cell. Biol. 3:871-880.


Herskowitz I. (1983).  Cellular differentiation cell lineages and transposable genetic cassettes in yeast.  Curr. Top. Dev. Biol. 18:1-14.

Herskowitz I. (1983).  Determination of yeast cell type. Symp. Soc. Dev. Biol. 41:65-75.

Herskowitz I., S. Roark and E. Lynch (1983).  Lambda (ThePoster).  In: Bacteriophage Lambda. II, Weisberg R., F.W. Stahl and J.W. Roberts, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

Hall M.N., L. Hereford and I. Herskowitz (1984).  Targeting of E. coli beta galactosidase to the nucleus in yeast.  Cell 36:1057-1065.

Friedman D.I., E.R. Olson, C. Georgopoulos, K. Tilly, I. Herskowitz and F. Banuett (1984).  Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda.  Microbiol. Rev. 48:299-325.

Stern M., R. Jensen and I. Herskowitz (1984).  Five SWI genes are required for expression of the HO gene in yeast.  J. Mol. Biol. 178:853-868.

Herskowitz I. and F. Banuett (1984).  Interaction of phage host and environmental factors in governing the lambda lysis-lysogeny decision.  Proceedings of the XV International Congress of Genetics (New Delhi 1983) Oxford and IBH Publishing Co., New Delhi, pp. 59-73.

Wilson K.L. and I. Herskowitz (1984).  Negative regulation of STE6 gene expression by the a2 product of yeast.  Mol. Cell. Biol. 4:2420-2427.

Jensen R.E. and I. Herskowitz (1984).  Directionality and regulation of cassette substitution in yeast.  Cold Spring Harbor Symp. Quant. Biol. 49:97-104.

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Simon M. and I. Herskowitz (1985).  Introduction.  In: Genome Rearrangement UCLA Symposia on Molecular and Cellular Biology Vol. 20 M. Simon and I. Herskowitz eds. Alan Liss Inc. New York xv-xix.

Johnson A.D. and I. Herskowitz (1985).  A repressor (MATa2 product) and its operator control expression of a set of cell type specific genes inyeast.  Cell 42:237-247.

Fields S. and I. Herskowitz (1985).  The yeast STE12 product is required for expression of two sets of cell-type-specific genes.  Cell 42:923-930.

Herskowitz I. (1985).  Yeast as the universal cell (News andViews).  Nature 316:678-679.

Herskowitz I. (1985).  Master regulatory loci in yeast and lambda.  Cold Spring Harbor Symp. Quant. Biol. 50:565-574.

Herskowitz I. (1986).  Cell type determination and mating type interconversion in yeast.  In: Cellular and Molecular Aspects of Developmental Biology Fougereau M. and R. Stora eds. Les Houches XLII 67-98.

Banuett F., M.A. Hoyt, L. McFarlane, H. Echols and I. Herskowitz (1986).  hflB a new Escherichia coli locus regulating lysogeny and the level of bacteriophage lambda cII protein.  J. Mol. Biol. 187:213-224.

Mitchell A.P. and I. Herskowitz (1986).  Activation of meiosis and sporulation by repression of the RME1 product in yeast.  Nature 319:738-742.

Wilson K.L. and I. Herskowitz (1986).  Sequences upstream of the STE6 gene required for its expression and regulation by the mating type locus in Saccharomyces cerevisiae.  Proc. Natl. Acad. Sci. USA 83:2536-2540.


Herskowitz I. (1986).  Specialized cell types in yeast:  Their use in addressing problems in cell biology.  In: Yeast Cell Biology Hicks J.B. ed. UCLA Symposia on Molecular and Cellular Biology Alan R. Liss Inc. New York 625-656.

Russell D.W., R. Jensen, M.J. Zoller, J. Burke, B. Errede, M. Smith and I. Herskowitz (1986).  Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream region.  Mol. Cell. Biol. 6:4281-4294.

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Powers S., S. Michaelis, D. Broek, S. Santa-Anna A., J. Field, I. Herskowitz and M. Wigler (1987).  RAM, a gene of yeast required for a functional modification of RAS proteins and mating pheromone a-factor.  Cell 47:413-422.

Sternberg P.W., M.J. Stern, I. Clark and I. Herskowitz (1987).  Activation of the yeast HO gene by release from multiple negative controls.  Cell 48: 567-577.

Herskowitz I. (1987).  A master regulatory locus that determines cell specialization in yeast.  The Harvey Lectures 81:67-92.

Rine J. and I. Herskowitz (1987).  Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae.  Genetics 116:9-22.

Herskowitz I. (1987).  Functional inactivation of genes by dominant negative mutations.  Nature 329:219-222.

Wilson K.L. and I. Herskowitz (1987).  STE16, a new gene required for pheromone production by a cells of Saccharomyces cerevisiae.  Genetics 115: 441-449.

Banuett F. and I. Herskowitz (1987).  Identification of polypeptides encoded by an Escherichia coli locus (hflA) that governs the lysis lysogeny decision of bacteriophage lambda.  J. Bacteriol. 169:4076-4085.

Herskowitz I. and L. Marsh (1987). Conservation of a receptor/signal transduction system.  Cell 50:995-996.

Fields S. and I. Herskowitz (1987).  Regulation by the yeast mating type locus of STE12, a gene required for cell type specific expression.  Mol. Cell. Biol. 7:3818-3821.

Michaelis S. and I. Herskowitz (1988).  The a-factor pheromone of Saccharomyces cerevisiae is essential for mating.  Mol. Cell. Biol. 8:1309-1318.

Banuett F. and I. Herskowitz (1988).  Ustilago maydis smut of maize.  In: Genetics of Phytopathogenic Fungi G.S. Sidhu ed. Advances in Plant Pathology 6 Academic Press London 427-455.

Marsh L. and I. Herskowitz (1988).  STE2 protein of Saccharomyces kluyveri is a member of the rhodopsin/beta adrenergic receptor family and is responsible for recognition of the peptide ligand a factor.  Proc. Natl. Acad. Sci. USA 85:3855-3859.

Herskowitz I. (1988).  The Hawthorne deletion twenty five years later.  Genetics 120:857-861.

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Herskowitz I. (1988).  The life cycle of the budding yeast Saccharomyces cerevisiae.  Microbiol. Rev. 52:536-553.

Marsh L. and I. Herskowitz (1988).  From membrane to nucleus: The pathway of signal transduction in yeast and its genetic control.  Cold Spring Harbor Symp. Quant. Biol. 53:557-565.

Andrews B.J. and I. Herskowitz (1989).  Identification of a DNA binding factor involved in cell cycle control of the yeast HO gene.  Cell 57:21-29.


Banuett F. and I. Herskowitz (1989).  Different a alleles of Ustilago maydis are necessary for maintenance of filamentous growth but not for meiosis.  Proc. Natl. Acad. Sci. USA 86:5878-5882.

Herskowitz I. (1989).  Negative growth factors in yeast: Genetic control of synthesis and response.  In: The Regulation of Proliferation and Differentiation in Normal and Neoplastic Cells, E. Frei III, ed. Academic Press Inc., NY, pp. 21-37.

Herskowitz I. (1989).  Multiple loci for resistance to negative growth factors in yeast.  In: Current Communications in Molecular Biology: Recessive Oncogenes and Tumor Suppression, W. Cavenee N. Hastie and E. Stanbridge, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 221-234.

Herskowitz I. (1989).  A regulatory hierarchy for cell specialization in yeast.  Nature 342:749-757.

Andrews B.J. and I. Herskowitz (1989).  The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription.  Nature 342:830-833.

Schulz B,. F. Banuett, M. Dah,l R. Schlesinger, W. Schaefer, T. Martin, I. Herskowitz and R. Kahmann (1990).  The b alleles of U. maydis whose combinations program pathogenic development code for polypeptides containing a homeodomain related motif.  Cell 60:295-306.

Neiman A.M., F. Chang, K. Komachi and I. Herskowitz (1990).  CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast.  Cell Regulation 1:391-401.

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Herskowitz I. and R.E. Jensen (1990).  Putting the HO gene to work: practical uses for mating
type switching.  Meth. Enzymol. 194:132-146.

Andrews B.J. and I. Herskowitz (1990).  Regulation of cell-cycle-dependent gene expression in yeast.  J. Biol. Chem. 265:14057-14060.

Wang H., I. Clar,k P.R. Nicholson, I. Herskowitz and D.J. Stillman (1990).  The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs.  Mol. Cell. Biol. 10:5927-5936.

Chang F. and I. Herskowitz (1990).  Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin CLN2.  Cell 63:999-1011.

Brenner S., W. Dove, I. Herskowitz and R. Thomas (1990).  Genes and development: molecular and logical themes.  Genetics 126:479-486.

Peterson C.L., W. Kruger and I. Herskowitz (1991).  A functional interaction between the C-terminal domain of RNA polymerase II and the negative regulator SIN1.  Cell 64:1135-1143.

Kruger W. and I. Herskowitz (1991).  A negative regulator of HO transcription SIN1 (SPT2) is a nonspecific DNA-binding protein related to HMG1.  Mol. Cell. Biol. 11:4135-4146.

Chant J. and I. Herskowitz (1991).  Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway.  Cell 65:1203-1212.

Chant J., K. Corrado, J.R. Pringle and I. Herskowitz (1991).  Yeast BUD5, encoding a putative GDP GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1.  Cell 65:1213-1224.

Marsh L., A.M. Neiman and I. Herskowitz (1991).  Signal transduction during pheromone response in yeast.  Ann. Rev. Cell Biol. 7:699-72


Ogas J., B.J. Andrews and I. Herskowitz (1991).  Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription.  Cell 66:1015-1026.

Covitz P.A., I. Herskowitz and A.P. Mitchell (1991).  The yeast RME1 gene encodes a putative zinc finger protein that is directly repressed by a1-a2.  Genes Dev. 5:1982-1989.

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Herskowitz I. and F. Chang (1991).  Arrest of the yeast cell cycle by a negative growth factor: antagonism of a G1 cyclin (CLN2) by FAR1.  In: Origins of Human Cancer: A Comprehensive Review, J. Brugge, T. Curran, E. Harlow and F. McCormick, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 35-43.

Herskowitz I., J. Ogas, B.J. Andrews and F. Chang (1991).  Regulators of synthesis and activity of the G1 cyclins of budding yeast.  Cold Spring Harbor Symp. Quant. Biol. 56:33-40.

Horvitz H.R. and I. Herskowitz (1992).  Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question.  Cell 68:1-20.

Peterson C.L. and I. Herskowitz (1992).  Characterization of theyeast SWI1, SWI2 and SWI3 genes, which encode a global activator of transcription.  Cell 68:573-583.

Chenevert J., K. Corrado, A. Bender, J. Pringle and I. Herskowitz (1992).  A yeast gene (BEM1) whose product contains two SH3 domains.  Nature 356:77-79.

Chang F. and I. Herskowitz (1992).  Phosphorylation of FAR1 in response to a-factor: a possible requirement for cell cycle arrest.  Mol. Cell Biol. 3:445-450.

Herskowitz I. (1992).  Yeast branches out.  Nature 357:190-191.

Herskowitz I. (1992).  Controlling elements mutable alleles and matin- type interconversion.  In: The Dynamic Genome: Barbara McClintock's Ideas in the Century of Genetics, N. Federoff and D. Botstein, eds., Cold Spring Harbor Laboratory Press, Cold Spring Harbor New York, pp. 289-297.

Hoffman F.M., P.W. Sternberg and I. Herskowitz (1992).  Learning about cancer genes through invertebrate genetics.  Curr. Opin. Genet. Dev. 2:45-52.

Lee R.T., C.L. Peterson, A.F. Calman, I. Herskowitz and J.J. O'Donnell (1992).  Cloning of a human galactokinase gene (GK2) on chromosome 15 by complementation in yeast.  Proc. Natl. Acad. Sci. USA 89:10887-10891.

Yoshinaga S.K., C.L. Peterson, I. Herskowitz and K.R. Yamamoto (1992).  Roles of the SWI1, SWI2 and SWI3 proteins for transcriptional enhancement by steroid receptors.  Science 258:1598-1604.

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Neiman A.M., B.J. Stevenson, H. P. Xu, G.F. Sprague Jr., I. Herskowitz, M. Wigler and S. Marcus (1992).  Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms.  Mol. Biol. Cell 4: 107-120.

Herskowitz I., J. Rine and J. Strathern. 1992.  Mating type determination and mating-type interconversion in Saccharomyces cerevisiae.  In: The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, E.W. Jones, J.R. Pringle and J.R. Broach, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NYk, pp. 583-656.

Herskowitz I., B. Andrews, W. Kruger, J. Ogas, A. Sil, C. Coburn and C. Peterson.  Integration of multiple regulatory inputs in the control of HO expression in yeast.  1992.  In: Transcriptional Regulation, S.L. McKnight and K.R. Yamamoto, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 949-974.


McElreavey K., E. Vilain, N. Abbas, I. Herskowitz and M. Fellous (1993).  A regulatory cascade hypothesis for mammalian sex determination: SRY represses a negative regulator of male development.  Proc. Natl Acad. Sci. USA 90: 3368-3372.

Peter M., A. Gartner, J. Horecka, G. Ammerer and I. Herskowitz (1993). FAR1 protein links the signalling pathway to the cell cycle machinery in yeast.  Cell 73:747-760.365:269-274.

Park H.-O., J. Chant and I. Herskowitz (1993). BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast. Nature 365:269-274.

Noble J.A., M.A. Innis, E.V. Koonin, K.E. Rudd, F. Banuett and I. Herskowitz (1993).  The Escherichia coli hflA locus encodes a putative GTP-binding protein and two membrane proteins, one of which contains a protease like domain.  Proc. Natl. Acad. Sci. USA 90:10866-10870.

Li J.J. and I. Herskowitz (1993).  Isolation of ORC6, a component of the yeast origin recognition complex by a one hybrid system.  Science 262:1870-1874.

Herskowitz J., J. Cuddihy and I. Herskowitz (1993). Double Talking Helix Blues (children's book).  Cold Spring Harbor Laboratory Press, Plainview, NY.

Chenevert J., N. Valtz and I. Herskowitz (1994).  Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae.  Genetics 136: 1287-1296.

Kaffman A., I. Herskowitz, R. Tjian and E.K. O’Shea (1994).  Phosphorylation of the transcription factor PHO4 by a cyclin CDK complex, PHO80-PHO85.  Science 263:1153-1156.

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Neiman A.M. and I. Herskowitz (1994).  Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11.  Proc. Natl. Acad. Sci. USA 91:3398-3402.

Banuett F. and I Herskowitz (1994).  Identification of Fuz7, a Ustilago maydis MEK/MAPKK homolog required for a-Locus-dependent an- independent steps in the fungal life cycle.  Genes Dev. 8:1367-1378.

Banuett F. and I. Herskowitz (1994).  Morphological transitions in the life cycle of Ustilago maydis and their genetic control by the a  and b loci.  Exper. Mycol. 18:247-266.

Peter M. and I. Herskowitz (1994).  Direct inhibition of the yeast cyclin dependent kinase Cdc28-Cln by Far1.  Science 265:1228-1231.

Santa Anna-Arriola S. and I. Herskowitz (1994).  Isolation and DNA sequence of the STE13 gene encoding dipeptidyl aminopeptidase.  Yeast 10:801-810.

Peter M. and I. Herskowtiz (1994). Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle.  Cell 79:181-184.

Espinoza F.H., J. Ogas, I. Herskowitz and D.O. Morgan (1994).  Cell cycle control by a complex of the cyclin HCs26 (PCL1) and the kinase PHO85.  Science 266:1388-1391.

Gerber M.R., A. Farrell, R.J. Deshaies, I. Herskowitz and D.O. Morgan (1995). Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins.  Proc. Natl. Acad. Sci. USA 92:4651-4655.

Herskowitz I. (1995). MAP kinase pathways in yeast: for mating and more.  Cell 80:187-197.

Chant J., M. Mischke, E. Mitchell, I. Herskowitz and J.R. Pringle (1995).  Role of Bud3p in producing the axial budding pattern of yeast.  J. Cell Biol. 129:767-778.


Valtz N., M. Peter and I Herskowitz (1995).  FAR1 is required for oriented polarization of yeast cells in response to mating pheromones.  J. Cell Biol. 131:863-873.

Kruger W. ,C.L. Peterson, A. Sil, C. Coburn, G. Arents, E.N. Moudrianakis and I. Herskowitz (1995). Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription. Genes Dev. 9:2770-2779.

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Herskowitz I., H.-O. Park, S. Sanders, N. Valtz and M. Peter (1995). Programming of cell polarity in budding yeast by endogenous and exogenous signals.  Cold Spring Harbor Symp. Quant. Biol. 60:717-727.

Sil A. and I. Herskowitz (1996). Identification of an asymmetrically localized determinant required for lineage specific transcription of the yeast HO gene. Cell 84:711-722.

Banuett F. and I Herskowitz (1996). Discrete developmental stages during teliospore formation in the corn smut fungus Ustilago maydis.  Development 122:2965-2976.

Sanders S.L. and I. Herskowitz (1996). The Bud4 protein of yeast required for axial budding is localized to the mother/budneck in a cell cycle dependent manner. J. Cell Biol. 134:413-427.

Valtz N. and I. Herskowitz (1996). Pea2 protein of yeast is localized to sites of polarized growth and is required for efficient mating and bipolar budding.  J. Cell Biol. 135:725-739.

Peter M., A.M. Neiman, H.-O. Park, M. van Lohuizen and I. Herskowitz (1996). Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J. 15:7046-7059.

Leberer E., J. Chenevert, T. Leeuw, D. Harcus, I. Herskowitz and D.Y. Thomas (1996). Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated pheromone signaling pathway to regulators of cell polarity. Mol. Gen. Genet. 252:608-621.

Park H.-O., E. Bi, J.R. Pringle and I. Herskowitz. (1997). Two active states of the Ras related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity.  Proc. Natl. Acad. Sci. USA 94:4463-4468.

Gray J.V., J.P Ogas, Y. Kamada, M. Stone, D.E. Levin and I. Herskowitz (1997). A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator.  EMBO J. 16:4924-4937.

Philips J. and I. Herskowitz (1997). Osmotic balance regulates cell fusion during mating in Saccharomyces cerevisiae. J. Cell Biol. 138:961-974.

Takizawa P.A., A. Sil, J.R. Swedlow, I. Herskowitz and R.D. Vale (1997). Actin dependent localization of an RNA encoding a cell-fate determinant in yeast.  Nature 389:90-93.

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Henchoz S., Y. Chi, B. Catarin, I. Herskowitz, R.J. Deshaies and M. Peter (1997). Phosphorylation and ubiquiti- dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev. 11:3046-3060.

Herskowitz I. (1997). Building organs and organisms: elements of morphogenesis exhibited by budding yeast. Cold Spring Harbor Symp. Quant. Biol. 62:57-63.

Shaham S., M.A. Shuman and I. Herskowitz (1998) Death-defying yeast identify novel apoptosis genes. Cell 92:425-427.


Herskowitz I. and F. W. Stahl (1998).  Genes to Cells in Mishima: meeting report. Genes to Cells 3:1-8.

Chu S. and I. Herskowitz (1998).  Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80. Mol. Cell 1:685-696.

Tabtiang R. and I. Herskowitz (1998). Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p dependent lacZ reporter gene in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:4707-4718.

O’Rourke S. and I. Herskowitz (1998) The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in S. cerevisiae.  Genes Dev. 12:2874-2886.

Chu S., J. DeRisi, M. Eisen, J. Mulholland, D. Botstein, P.O. Brown and I. Herskowitz (1998). The transcriptional program of sporulation in budding yeast. Science 282:699-705.

Philips J. and I. Herskowitz (1998) Identification of Kel1p, a Kelch domain-containing protein involved in cell fusion and  morphology in Saccharomyces cerevisiae. J. Cell Biol. 143:375-389.

Herskowitz I. (1998). Coming early to the late genes. Curr. Biol. 8:R827-R828.

Butty A.C., P.M. Pryciak, L.S. Huan,g I. Herskowitz and M. Peter (1998). The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science 282:1511-1516.

Sanders S.L., M. Gentzsch, W. Tanner and I. Herskowitz (1999). O-glycosylation of AxI1/Bud1Op by Pmt4p is required for its stability, localization and function in daughter cells. J. Cell Biol 145:1177-1188.

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Park H.-O., A. Sanson and I. Herskowitz (1999). Localization of Bud2 protein a GTPase activating protein necessary for programming cell polarity in yeast to the presumptive bud site. Genes Dev. 13:1912-1917.

Grether M. and I. Herskowitz (1999) Genetic and biochemical characterization of the yeast Spo12 protein. Mol. Biol. Cell 10:3689-3703.

Schlumpberger M., H. Wille, M.A. Baldwin, D.A. Butler, I. Herskowitz and S. B. Prusiner (2000).  The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein.  Protein Sci. 9:1-12.

O'Shea E.K. and I. Herskowitz (2000) The ins and outs of cell polarity decisions. Nat. Cell Biol. 2:E39-E40.

Maxon M.E. and I. Herskowitz (2001) Ash1p is a site specific DNA binding protein that actively represses transcription. Proc. Natl. Acad. Sci. USA 98:1495-1500.

Tadauchi T., K. Matsumoto, I. Herskowitz and K. Irie (2001).  Post Transcriptional Regulation of HO Through the HO 3’ UTR by Mpt5, a Yeast Homolog of Pumilio and FBF.  EMBO J. 20:552-561.

Schlumpberger M.S.B., S.B. Prusiner and I. Herskowitz (2001). The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein.  Protein Science 9:1-12.

Schlumpberger M S.B. Prusiner and I. Herskowitz (2001). Induction of distinct [URE3] yeast prion strains.  Mol. Cell. Biol. 21:7035-7046.

Herskowitz I. (2001) Cassette Model. In: Encyclopedia of Genetics,  Brenner S. and Miller J.H., eds. Academic Press, New York, NY, pp. 275-278.

O’Rourke S.M. and I. Herskowitz (2002).  A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel to the Sho1 branch.  Mol. Cell. Biol. 22:4739-4749.

Irie K., T. Tadauch,i P.A. Takizawa, R.D. Vale, K. Matsumoto and I. Herskowitz (2002).  The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast.  EMBO J. 21:1158-1167.

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McBride H.J., A. Sil, V. Measday, Y. Yu, J. Moffat, M.E. Maxon, I. Herskowitz, B. Andrews and D.J. Stillman (2001).  The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae. Mol. Microbiol. 42:345-353.

Herskowitz I. and E. O’Shea (2002).  The 2001 Thomas Hunt Morgan Medal.  Yasuji Oshima. Genetics 160:367-368.

Herskowitz I. (2002).  Regulating natural health products (letter).  Science 296:46-47.

O'Rourke S.M., I. Herskowitz and E.K. O'Shea (2002).  Yeast go the whole HOG for the hyperosmotic response.  Trends Genet. 18:405-12.

Leabman M.K., C.C. Huang, M. Kawamoto, S.J. Johns, D. Stryke, T.E. Ferrin, J. DeYoung, T. Taylor, A.G. Clark, I. Herskowitz and K.M. Giacomini (2002).  Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function.  Pharmacogenetics 12:395-405.

Ishida S., J. Lee, D.J. Thiele and I. Herskowitz (2002).  Uptake of the anticancer drug cisplatin mediated by the copper transporter, Ctr1, in yeast and mammals.  Proc. Natl. Acad. Sci. USA 99:14298-302.

Banuett F. and I. Herskowitz (2002).  Bud morphogenesis and the actin and microtubule cytoskeletons during budding in the corn smut fungus Ustilago maydis.  Fungal Genet. Biol. 37:149-70. 

Stryke D., C.C. Huang, M. Kawamoto, S.J. Johns, E.J. Carlson, J.A. Deyoung, M.K. Leabman, I. Herskowitz, K.M. Giacomini  and T.E. Ferrin (2003).  SNP analysis and presentation in the Pharmacogenetics of Membrane Transporters Project.  Pac. Symp. Biocomput. 535-47.

Clyne R.K., V.L. Katis, L. Jessop, K.R. Benjamin, I. Herskowitz, M. Lichten and K. Nasmyth (2003).  Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I.  Nat. Cell Biol. 5:480-5.

Leabman M.K., C.C. Huang, J. DeYoung,  E.J. Carlson, T.R. Taylor, M. De La Cruz, S.J. Johns, D. Stryke, M. Kawamoto, T.J. Urban, D.L. Kroetz, T.E. Ferrin, A.G. Clark, N. Risc,h I. Herskowitz, K.M. Giacomini and Pharmacogenetics of Membrane Transporters Investigators (2003).  Natural variation in human membrane transporter genes reveals evolutionary and functional constraints.  Proc. Natl. Acad. Sci. USA 100:5896-5901.

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Shu Y., M.K. Leabman, B. Feng, L.M. Mangravite, C.C. Huang, D. Stryke, M. Kawamoto, S.J. Johns, J. DeYoung,  E. Carlson, T.E. Ferrin, I. Herskowitz, K.M. Giacomini and Pharmacogenetics of Membrane Transporters Investigators (2003).  Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1.  Proc. Natl. Acad. Sci. USA 100:5902-5907.

Osato D.H., C.C. Huang, M. Kawamoto, S.J. Johns, D. Stryke, J. Wang, T.E. Ferrin, I. Herskowitz and K.M. Giacomini  (2003).  Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1.  Pharmacogenetics 13:297-301.


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