Primary cilia proteome, intraflagellar transport, ciliogenesis, and mechanobiology of cilia.
Organelle size control using the yeast vacuole as a model system.
I utilize methods in molecular biology, cell biology, chemical biology and biochemistry to understand signaling mechanisms that regulate the structure and function of cilia and flagella in Chlamydomonas and mammalian cells. Current interests include flagellar regulation involving GPCRs, MAP kinases and actin.
Role of calcium signaling and protein kinases in single cell regeneration in Stentor
Role of mRNA localization and RNA binding proteins in single cell regeneration in Stentor
Role of microtubule cytoskeleton and motors in single cell regeneration in Stentor
Systems biology of mucus and mucociliary interactions using Planarian flatworms as a model system
Developing Stentor as a model organism for studying single cell regeneration. Role of polarity proteins and centriole duplication in Stentor regeneration.
Regulation and Control of Organelle Morphology, Implications of Organelle Morphology for Cellular Behavior in Mammalian Cell Systems
Marshall Lab Alumni
Associate Professor, National Institute for Basic Biology, Okazaki Japan
Assistant Professor, UC Irvine
Group Leader, Institute Jacques Monod Paris, France
Assistant Professor, National Institute of Biological Science (NIBS), Beijing, China
Former Ph.D. Students
Assistant Professor, Quinnipiac University
soon starting as Assistant Professor, Dept. Biology, Stanford University
Postdoc at Max Planck Institute, Martinsried, Germany
Biotech Entrepreneur - founder of EvolveMol, SoilGen, and co-founder of uBiome
Bowes Fellow at UC Berkeley and co-founder uBiome
Former Grad Student
Former Research Associates
Christopher Baker former SRA, currently grad student at UCSF Tetrad Program
Roshan Karki former SRA, currently grad student at Yale MCDB Program
Afsaneh Zolfaghari former SRA, currently grad student at Harvard School of Public Health
Ivan Zamora Former SRA