Projects focusing on zebrafish liver development include:

• Screening for mutants with liver defects
• Characterizing liver defects and identifying genetic lesions in novel mutants
• Characterizing intrahepatic biliary tract development

pancreas

Projects focusing on zebrafish pancreas development include:

• Screening for mutants with pancreatic defects
• Characterizing pancreatic defects and identifying genetic lesions in novel zebrafish mutants
• Analyzing early differentiation of pancreatic beta cells
• Determining how growth factors from mesenchymal tissue contribute to pancreatic development

gut & visceral smooth muscle

Lab members studying the zebrafish gut and visceral smooth muscle: Michel Bagnat, Isla Cheung

early endoderm

regeneration

• Screening for mutants with defects in intestinal absorption of lipids
• Screening for mutants with excess accumulation of lipids in the liver (steatosis)
• Characterizing intestinal and liver defects using imaging, biochemistry and pharmacology; and identifying genetic lesions in novel mutants