UCSF Department of Biochemistry & Biophysics

Mustafa Aydogan, PhD

Sandler Fellow

Dr. Aydogan is fascinated by how biological time is regulated across different scales, with a particular interest in the regulation of organelle biogenesis. He carried out his doctoral work at the University of Oxford to study how centriole biogenesis is regulated in space and time. In particular, he discovered that an autonomous clock controls the timing of centriole formation independently of, but in entrainment with, the principal Cdk/Cyclin cell-cycle oscillator. This finding challenges the current model of how cell cycle is regulated and opens a potential new avenue of research to explore whether other such autonomous clocks exist in the cell. Aydogan Lab currently focuses on timing mechanisms that may be at play in the biogenesis of other organelles. They use state-of-the-art techniques in live super-resolution microscopy, combined with genetics, biochemistry, biophysics and mathematical modelling, to address biological phenomena.

UCSF Profiles Page for Mustafa Aydogan, PhD
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